eLetters is an online forum for ongoing peer review. Submission of eLetters are open to all . Please read our guidelines before submitting your own eLetter.
Research ArticleBIOMEDICAL ENGINEERING
Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation
- Craig S. Schneider1,2,3,*,
- Qingguo Xu1,4,*,
- Nicholas J. Boylan1,3,*,
- Jane Chisholm1,3,
- Benjamin C. Tang1,3,†,
- Benjamin S. Schuster1,5,‡,
- Andreas Henning1,3,
- Laura M. Ensign1,2,3,4,
- Ethan Lee3,
- Pichet Adstamongkonkul5,
- Brian W. Simons6,7,
- Sho-Yu S. Wang1,3,
- Xiaoqun Gong1,8,
- Tao Yu1,5,
- Michael P. Boyle9,
- Jung Soo Suk1,4,5,§ and
- Justin Hanes1,2,3,4,5,§
- 1The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.
- 2Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD 21218, USA.
- 3Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
- 4Wilmer Eye Institute, Johns Hopkins Medical Institute, Baltimore, MD 21287, USA.
- 5Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
- 6Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
- 7Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
- 8School of Life Sciences, Tianjin University, Tianjin 300072, People‘s Republic of China.
- 9Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
- ↵§Corresponding author. Email: jsuk{at}jhmi.edu (J.S.S.); hanes{at}jhmi.edu (J.H.)
See allHide authors and affiliations
Science Advances 05 Apr 2017:
Vol. 3, no. 4, e1601556
DOI: 10.1126/sciadv.1601556
Vol. 3, no. 4, e1601556
DOI: 10.1126/sciadv.1601556
Craig S. Schneider
The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD 21218, USA.Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
Qingguo Xu
The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.Wilmer Eye Institute, Johns Hopkins Medical Institute, Baltimore, MD 21287, USA.
Nicholas J. Boylan
The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
Jane Chisholm
The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
Benjamin C. Tang
The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
Benjamin S. Schuster
The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Andreas Henning
The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
Laura M. Ensign
The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD 21218, USA.Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.Wilmer Eye Institute, Johns Hopkins Medical Institute, Baltimore, MD 21287, USA.
Ethan Lee
Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
Pichet Adstamongkonkul
Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Brian W. Simons
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Sho-Yu S. Wang
The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
Xiaoqun Gong
The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.School of Life Sciences, Tianjin University, Tianjin 300072, People‘s Republic of China.
Tao Yu
The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Michael P. Boyle
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Jung Soo Suk
The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.Wilmer Eye Institute, Johns Hopkins Medical Institute, Baltimore, MD 21287, USA.Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Justin Hanes
The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD 21218, USA.Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.Wilmer Eye Institute, Johns Hopkins Medical Institute, Baltimore, MD 21287, USA.Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Submit a Response to This Article
No eLetters have been published for this article.